Identification

Author

Marathe A, Lewis B, Barrett C, Chen J, Marathe M, et al.

Title

Comparing effectiveness of top-down and bottom-up strategies in containing Influenza

Year

2011

Publication type

Article

Journal

Plos ONE

Created

2014-04-07 19:51:07+00:00

Modified

2016-07-27 17:53:32.105745+00:00

Details

Volume

6

Number

9

Access

Language

English

URL http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0025149
DOI

10.1371/journal.pone.0025149

Accessed

2016-06-28

Extended information

Abstract

This research compares the performance of bottom-up, self-motivated behavioral interventions with top-down interventions targeted at controlling an “Influenza-like-illness”. Both types of interventions use a variant of the ring strategy. In the first case, when the fraction of a person's direct contacts who are diagnosed exceeds a threshold, that person decides to seek prophylaxis, e.g. vaccine or antivirals; in the second case, we consider two intervention protocols, denoted Block and School: when a fraction of people who are diagnosed in a Census Block (resp., School) exceeds the threshold, prophylax the entire Block (resp., School). Results show that the bottom-up strategy outperforms the top-down strategies under our parameter settings. Even in situations where the Block strategy reduces the overall attack rate well, it incurs a much higher cost. These findings lend credence to the notion that if people used antivirals effectively, making them available quickly on demand to private citizens could be a very effective way to control an outbreak.