Identification

Author

Lunde TM, Korecha D, Loha E, Sorteberg A, Lindtjorn B

Title

A dynamic model of some malaria-transmitting anopheline mosquitoes of the Afrotropical region. I. Model description and sensitivity analysis

Year

2013

Publication type

Article

Journal

Malaria Journal

Created

2013-08-02 22:28:07+00:00

Modified

2016-06-13 16:39:40.156813+00:00

Details

Volume

12

Number

28

Access

Language

English

URL http://www.malariajournal.com/content/pdf/1475-2875-12-28.pdf
Accessed

2016-06-13

Extended information

Abstract

Background: Most of the current biophysical models designed to address the large-scale distribution of malaria
assume that transmission of the disease is independent of the vector involved. Another common assumption in these
type of model is that the mortality rate of mosquitoes is constant over their life span and that their dispersion is
negligible. Mosquito models are important in the prediction of malaria and hence there is a need for a realistic
representation of the vectors involved.
Results: We construct a biophysical model including two competing species, Anopheles gambiae s.s. and Anopheles
arabiensis. Sensitivity analysis highlight the importance of relative humidity and mosquito size, the initial conditions
and dispersion, and a rarely used parameter, the probability of finding blood. We also show that the assumption of
exponential mortality of adult mosquitoes does not match the observed data, and suggest that an age dimension can
overcome this problem.
Conclusions: This study highlights some of the assumptions commonly used when constructing mosquito-malaria
models and presents a realistic model of An. gambiae s.s. and An. arabiensis and their interaction. This new mosquito
model, OMaWa, can improve our understanding of the dynamics of these vectors, which in turn can be used to
understand the dynamics of malaria.