Identification

Author

Jamieson DJ, Kourtis AP, Bell M, Rasmussen SA

Title

Lymphocytic Choriomeningitis Virus: An emerging obstetric pathogen?

Year

2006

Publication type

Article

Journal

Elsevier

Created

2015-07-30 16:51:20.048683+00:00

Modified

2016-08-10 18:24:32.448794+00:00

Details

Volume

194

Pages

1532-1536

Access

Language

English

URL http://www.sciencedirect.com/science/article/pii/S0002937805026025
DOI

10.1016/j.ajog.2005.11.040

Accessed

2016-07-07

Extended information

Abstract

A report in May 2005 from the Centers for Disease Control and Prevention describing a cluster of lymphocytic choriomeningitis virus (LCMV) infections among 4 solid organ recipients has increased awareness of and clinical interest in this pathogen. Human infection with LCMV results from direct or indirect contact with rodents. LCMV has particular relevance to obstetrics, as it is likely an under-recognized abortifacient and fetal teratogen. There have been 54 cases of congenital LCMV reported since 1955, with 34 of the cases diagnosed since 1993. Chorioretinitis and hydrocephalus are the predominant characteristics among children diagnosed with congenital LCMV infection. Obstetricians should educate their pregnant patients about the risks of exposure to laboratory, pet, and wild rodents.